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Probenecid causes reduced excretion of cefalexin leading to increased plasma concentrations.

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Pregnant patients hospitalized in a secondary case-referral center with intense pruritus and abnormal serum levels of bile salts and aminotransferases, detected before week 33 of pregnancy, were randomly assigned to receive ursodeoxycholic acid, 1 g per day orally, or an identical placebo, until delivery, in a double-blind study.

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The bioequivalence study was conducted on each of five different days, separated by at least a 1-week period.

Hi Eugene, thanks for taking the time to post your latest results.

Studies are now underway to define the precise mechanism of this proapoptotic effect of UDCA.

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