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Secondary outcomes included ongoing pregnancy rate (OPR, pregnancy beyond 12 weeks of gestation, as confirmed by foetal heart activity on an ultrasound), and miscarriage rate (MR, the failure to achieve live birth after a positive β-hCG test).

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Some medications that are part of a course of IVF treatment include: Lupron, Ganirelix and Cetrotide for supression; Gonal-F, Follistim, Menopur, and Bravelle for stimulation; Endometrin and Crinone for progesterone supplementation; Vivelle, Minivelle and Estrace for estrogen supplementation.

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Larsson S, Svedmyr N "Bronchodilating effect and side effects of beta2- adrenoceptor stimulants by different modes of administration (tablets, metered aerosol, and combinations thereof).

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MENOPUR is a potent gonadotropic substance capable of causing Ovarian Hyperstimulation Syndrome (OHSS), with or without pulmonary or vascular complications, in women undergoing therapy for infertility.

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Efficacy was assessed on the endpoint of ongoing pregnancies, defined as the presence of at least one fetal heartbeat seen on ultrasound at 6 weeks post-embryo transfer.

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Progesterone decreases myometrial responsiveness by inhibiting estrogen receptor-α expression, and its byproducts competitively bind to oxytocin receptors and decrease oxytocin-induced contractility.

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ENDOMETRIN should not be used in individuals with any of the following conditions: previous allergic reactions to progesterone or any of the ingredients of ENDOMETRIN, known missed abortion or ectopic pregnancy, liver disease, known or suspected breast cancer, active arterial or venous thromboembolism or severe thrombophlebitis, or a history of these events.

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February 2008, combined the results of many of these smaller studies.

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Nonsupplemented luteal phase characteristics after the administration of recombinant human chorionic gonadotropin, recombinant luteinising hormone, or gonadotropin-releasing hormone (GnRH) agonist to induce final oocyte maturation in in vitro fertilization patients after ovarian stimulation with recombinant follicle-stimulating hormone and GnRH antagonist cotreatment.

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Note: Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

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Source: According to data from Wolters Kluwer Pharma Solutions, Source Pharmaceutical Audit Suite, January 2010 to July 2010, inclusive of reproductive endocrinologist specialty only.

Discontinue treatment if Hb is at or above 11.

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Keep all medicine out of the reach of children.

Unfortunately, during a natural cycle, we cannot control the day of ovulation.

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Once MENOPUR has been dissolved, it should be used immediately and any unused MENOPUR should be safely discarded.

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